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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SH3BP1 All Species: 8.18
Human Site: S586 Identified Species: 20
UniProt: Q9Y3L3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3L3 NP_061830.3 701 75713 S586 Q V S G S R S S P P A P P L P
Chimpanzee Pan troglodytes XP_515119 701 75665 S586 Q V S G S R S S P P A P P L P
Rhesus Macaque Macaca mulatta XP_001088993 757 82612 S638 A S P K V T R S P P E T A A P
Dog Lupus familis XP_538386 703 77033 T584 A S P K V S R T P S E A A T P
Cat Felis silvestris
Mouse Mus musculus P55194 601 65242 M487 P A P A R P T M P P P Q P S S
Rat Rattus norvegicus Q99N37 858 93735 P737 P R L G E Q G P E P G P T P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521066 476 51957 N362 E E W I Q A S N I Q D Q D K R
Chicken Gallus gallus XP_428489 626 68021 T512 Q P L S P V V T K P S P E A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001108378 535 59728 E421 K T E G S L A E M A A T T S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDS5 740 83067 Q615 K L K P D V P Q K P L L P K R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 75.1 74.8 N.A. 70.6 37.6 N.A. 30.2 59.2 N.A. 38.6 N.A. 26.3 N.A. N.A. N.A.
Protein Similarity: 100 99.5 78.1 79.2 N.A. 76.4 52.3 N.A. 40 71.6 N.A. 54.4 N.A. 44.1 N.A. N.A. N.A.
P-Site Identity: 100 100 26.6 13.3 N.A. 20 26.6 N.A. 6.6 20 N.A. 20 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 20 N.A. 26.6 33.3 N.A. 20 33.3 N.A. 33.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 10 0 10 0 10 10 0 0 10 30 10 20 20 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 0 10 0 10 0 0 % D
% Glu: 10 10 10 0 10 0 0 10 10 0 20 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 40 0 0 10 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 20 0 10 20 0 0 0 0 20 0 0 0 0 20 0 % K
% Leu: 0 10 20 0 0 10 0 0 0 0 10 10 0 20 0 % L
% Met: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 20 10 30 10 10 10 10 10 50 70 10 40 40 10 50 % P
% Gln: 30 0 0 0 10 10 0 10 0 10 0 20 0 0 0 % Q
% Arg: 0 10 0 0 10 20 20 0 0 0 0 0 0 0 20 % R
% Ser: 0 20 20 10 30 10 30 30 0 10 10 0 0 20 10 % S
% Thr: 0 10 0 0 0 10 10 20 0 0 0 20 20 10 0 % T
% Val: 0 20 0 0 20 20 10 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _